Development of a Biocompatible Matrix for Oral Delivery of Pharmaceutical Agents
As part of an applied research initiative led by the Global Trials Research Center, an innovative technology was developed for the oral delivery of pharmaceutical agents. This system is designed to ensure both the stability and controlled release of active compounds in the oral cavity and stomach.
Natural plant-based ingredients were selected as the foundation for the carrier matrix, aligning with current demands for ecological sustainability and biocompatibility. Through a series of specialized technological processes, a universal matrix was created from grain-based materials. This matrix transforms into an elastic, stable substance with a texture similar to chewing gum.
When chewed, the matrix stimulates salivation and facilitates the absorption of active pharmaceutical ingredients without the need for water. This opens the door to dual-action formulations—allowing absorption through both the oral mucosa and the gastrointestinal tract. The matrix is pleasant-tasting, soft in texture, mechanically stable, and can be safely swallowed without harm.
In collaboration with a partner laboratory, several test samples of edible chewing gum were developed using our patented matrix technology. These samples were tested on a group of 20 volunteers, yielding 100% positive feedback regarding comfort, taste, and ease of use. We believe this unexpected breakthrough holds significant promise in light of emerging ecological and consumer trends that prioritize natural ingredients, sustainability, and convenience.
Beyond pharmaceutical applications, the technology shows potential in the food industry. The matrix can be used to produce edible grain-based chewing gum as well as functional low-calorie snacks with customizable properties.
The production method and the matrix itself are protected under intellectual property law. Patent applications have been filed in the United States and the European Union.
Grain-Based Matrix: Emerging Natural Materials for the Future
